Scientific Methodology

Calculations and recommendations are grounded in peer-reviewed research and validated clinical algorithms, specifically designed for functional medicine practice

Institute for Functional Medicine Framework

Our platform is built specifically for practitioners trained in IFM principles, integrating the core concepts of systems biology and personalized medicine with advanced risk assessment technology.

Antecedents, Triggers, and Mediators (ATM) analysis

Seven core physiological systems assessment

Root cause identification and sequencing

Personalized therapeutic intervention protocols

Functional Systems

Assimilation

Biotransformation & Elimination

Defense & Repair

Structural Integrity

Communication

Energy

Transport

Validated Risk Algorithms

Cardiovascular Assessment

ASCVD Risk Estimator Plus

American College of Cardiology/American Heart Association

Framingham Risk Score

Framingham Heart Study validated algorithms

Reynolds Risk Score

Enhanced prediction with inflammatory markers

Metabolic & Aging Analysis

Phenotypic Age Calculator

Multi-biomarker biological age assessment

Klemera-Doubal Method

Validated biological age calculation

FINDRISC Algorithm

Diabetes risk assessment and prevention

Research Citations

Recommendations include primary literature citations and evidence grades, ensuring transparency and clinical confidence